Roesel, Johannes L.: search on Z-Library

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1

Aromatic Interactions with Phenylalanine 691 and Cysteine 828: A Concept for FMS-like Tyrosine Kinase-3 Inhibition. Application to the Discovery of a New Class of Potential Antileukemia Agents

Furet, Pascal, Bold, Guido, Meyer, Thomas, Roesel, Johannes, Guagnano, Vito

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 193 KB

english, 2006

2

Tyrosine Phosphorylation of Mitochondrial Pyruvate Dehydrogenase Kinase 1 Is Important for Cancer Metabolism

Taro Hitosugi, Jun Fan, Tae-Wook Chung, Katherine Lythgoe, Xu Wang, Jianxin Xie, Qingyuan Ge, Ting-Lei Gu, Roberto D. Polakiewicz, Johannes L. Roesel, Georgia Z. Chen, Titus J. Boggon, Sagar Lonial, H

Journal:

Year:

2011

Language:

english

File:

PDF, 1.99 MB

english, 2011

3

Novel Spirodihydrobenzofuranlactams as Antagonists of Endothelin and as Inhibitors of HIV-1 Protease Produced by Stachybotrys sp. I. Fermentation, Isolation and Biological Activity.

ROGGO, BARBARA E., PETERSEN, FRANK, SiLLS, MATTHEW, ROESEL, JOHANNES L., MOERKER, THÉOPHILE, PETER, HEINRICH H.

Journal:

The Journal of Antibiotics

Year:

1996

Language:

english

File:

PDF, 573 KB

english, 1996

4

Thoracic staging with18F-FDG PET/MR in non-small cell lung cancer – does it change therapeutic decisions in comparison to18F-FDG PET/CT?

Schaarschmidt, Benedikt M., Grueneisen, Johannes, Metzenmacher, Martin, Gomez, Benedikt, Gauler, Thomas, Roesel, Christian, Heusch, Philipp, Ruhlmann, Verena, Umutlu, Lale, Antoch, Gerald, Buchbender,

Journal:

European Radiology

Year:

2017

Language:

english

File:

PDF, 793 KB

english, 2017

5

Interleukin-12 and interleukin-18 change ICAM-I expression, and enhance natural killer cell mediated cytolysis of human osteosarcoma cells

Liebau, Christian, Merk, Harry, Schmidt, Sebastian, Roesel, Christian, Karreman, Christiaan, Prisack, Johannes Bernd, Bojar, Hans, Baltzer, Axel Wa

Journal:

Cytokines Cellular & Molecular Therapy

Year:

2002

Language:

english

File:

PDF, 745 KB

english, 2002

6

Cloning, expression and purification of a recombinant poly-histidine-linked HIV-1 protease

Andreas Leuthardt, Johannes L. Roesel

Journal:

Year:

1993

Language:

english

File:

PDF, 579 KB

english, 1993

7

Sulfonylbenzoyl-nitrostyrenes: Potential bisubstrate type inhibitors of the EGF-receptor tyrosine protein kinase

Traxler, Peter M., Wacker, Oskar, Bach, Ha L., Geissler, Johanna F., Kump, Wilhelm, Meyer, Thomas, Regenass, Urs, Roesel, Johannes L., Lydon, Nicholas

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 3.43 MB

english, 1991

8

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants

Maria Debiec-Rychter, Jan Cools, Herlinde Dumez, Raf Sciot, Michel Stul, Nicole Mentens, Hilde Vranckx, Bartosz Wasag, Hans Prenen, Johannes Roesel, Anne Hagemeijer, Allan Van Oosterom, Peter Marynen

Journal:

Gastroenterology

Year:

2005

Language:

english

File:

PDF, 416 KB

english, 2005

9

[(Alkylamino)methyl]acrylophenones: Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase

Traxler, Peter, Trinks, Uwe, Buchdunger, Elisabeth, Mett, Helmut, Meyer, Thomas, Mueller, Marcel, Regenass, Urs, Roesel, Johannes, Lydon, Nicholas

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.05 MB

english, 1995

10

Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice

Jean-Christophe Leroux, Eric Doelker, Robert Gurny, Robert Cozens, Johannes L. Roesel, Bruno Galli, Frank Kubel

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 562 KB

english, 1995

11

Non-Covalent Inhibitors of the 20S Proteasome

García-Echeverría, Carlos, Imbach, Patricia, Roesel, Johannes, Fuerst, Peter, Lang, Marc, Guagnano, Vito, Noorani, Maria, Zimmermann, Johann, Furet, Pascal

Journal:

CHIMIA International Journal for Chemistry

Year:

2003

Language:

english

File:

PDF, 83 KB

english, 2003

12

Comparison of the kinase profile of midostaurin (Rydapt®) with that of its predominant metabolites

Manley, Paul William, Caravatti, Giorgio, Furet, Pascal, Roesel, Johannes, Tran, Phi, Wagner, Trixie, Wartmann, Markus

Journal:

Year:

2018

Language:

english

File:

PDF, 2.62 MB

english, 2018

13

Investigation into CYP3A4-mediated drug–drug interactions on midostaurin in healthy volunteers

Dutreix, Catherine, Munarini, Florence, Lorenzo, Sebastien, Roesel, Johannes, Wang, Yanfeng

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 443 KB

english, 2013

14

pH-Sensitive Nanoparticles: An Effective Means to Improve the Oral Delivery of HIV-1 Protease Inhibitors in Dogs

Jean-Christophe Leroux, Robert M. Cozens, Johannes L. Roesel, Bruno Galli, Eric Doelker, Robert Gurny

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 510 KB

1996

15

Entry into a New Class of Potent Proteasome Inhibitors Having High Antiproliferative Activity by Structure-Based Design

Furet, Pascal, Imbach, Patricia, Noorani, Maria, Koeppler, Juergen, Laumen, Kurt, Lang, Marc, Guagnano, Vito, Fuerst, Peter, Roesel, Johannes, Zimmermann, Johann, García-Echeverría, Carlos

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 203 KB

english, 2004

16

HIV-1 Protease Inhibitors: Development, Status, and Potential Role in the Treatment of AIDS

Marc Lang, Johannes Roesel

Journal:

Archiv der Pharmazie

Year:

1993

Language:

english

File:

PDF, 396 KB

english, 1993

17

Novel β-lactam derivatives: Potent and selective inhibitors of the chymotrypsin-like activity of the human 20S proteasome

Patricia Imbach, Marc Lang, Carlos García-Echeverría, Vito Guagnano, Maria Noorani, Johannes Roesel, Francis Bitsch, Grety Rihs, Pascal Furet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 334 KB

english, 2007

18

3-Alkanoyl-5-hydroxymethyl tetronic acid homologues and resistomycin: New inhibitors of HIV-1 protease. I. Fermentation, isolation and biological activity.

ROGGO, BARBARA E., PETERSEN, FRANK, DELMENDO, RON, JENNY, HANS-BEAT, PETER, HEINRICH H., ROESEL, JOHANNES

Journal:

The Journal of Antibiotics

Year:

1994

Language:

english

File:

PDF, 361 KB

english, 1994

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